Chronic Atrophic Gastritis
Conditions
Interventions
Experimental group:Fortifying the Spleen,Clearing heat,Activating Blood Method
Sponsors
The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Age 18-65 years old, gender without limitation; (2) the diagnosis of chronic atrophic gastritis was confirmed by gastroendoscopy and gastric mucosa histopathology.At least one piece of histopathological findings showed moderate or severe intestinal metaplasia with or without intraepithelial neoplasia; (3) TCM syndrome was confirmed by standard syndrome differentiation; (4) Hp negative was diagnosied by rapid urease assay or 13C breath test or 14C breath test within nearly 1 month; (5) Be able to normal verbal communication; (6) Auqired the informed consent and willing to be a volunteer.
Exclusion criteria
Exclusion criteria: (1) Participating in other drug treatment studies within the nearly one month; (2) Combined with autoimmune gastritis (type A chronic atrophic gastritis), peptic ulcer (stage A1 -H2), reflux esophagitis, gastric polyp, hypertrophic gastritis, ulcerative colitis, history of gastrointestinal surgery and other disease; (3) Gastric mucosal high-grade intraepithelial neoplasia, gastrointestinal mucosal lesions suspected malignant transformation, gastrointestinal tumors; (4) Nearly 5 years of surgery, radiotherapy, chemotherapy of malignant tumors; (5) Combined with serious organic diseases.Such as: heart (cardiac functionNYHIII-IV, hemodynamic unstable myocardial infarction, etc.), liver (decompensated stage of liver cirrhosis, etc.), kidney (chronic renal failure, uremia stage, etc.), lung (tuberculosis, acute attack of asthma, pulmonary infection, etc.), autoimmune system (active stage of systemic lupus erythematosus), etc.; (6)Allergic constitution or allergic to a variety of drugs; (7) with severe mental illness so as to unable to cooperate with researchers, such as schizophrenia, depression, anxiety, dementia and so on; (8) pregnant, breast feeding women; (9) without cooperation of investigation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Histopathology; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gastroscopy evaluation;Syndrome efficacy evaluation;Symptom Assessment;Quality of life assessment;Anxiety and depression evaluation;Economic evaluation; | — |
Countries
China
Contacts
Public ContactFengbin Liu
The First Affiliated Hospital, Guangzhou University of Chinese Medicine
Outcome results
None listed