Hyperalgesia induced by remifentanil
Conditions
Interventions
Group 1:Lidocaine 1mg/kg
Group 2:Lidocaine 1.5mg/kg
Group 3:Dizocin 0.1mg/kg
Control group:saline
Sponsors
Yijishan Hospital affiliated to Southern Anhui Medical College
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Aged 20 - 60 years old, BMI 18 = 26 kg/m 2,ASA grade I or II.
Exclusion criteria
Exclusion criteria: Patients with any disease of following will be excluded: abnormal liver and kidney function, metabolic diseases such as hypertension, diabetes, hyperthyroidism, history of chronic pain, history of opioid addiction, history of mental illness and cognitive dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative VAS scores;The time of the first need for analgesia;Total amount of postoperative analgesics required;Occurrence of postoperative complications (nausea, vomiting, respiratory depression, chills, etc.); | — |
Secondary
| Measure | Time frame |
|---|---|
| Total amount of remifentanil and propofol during operation;Operation time, recovery time and extubation time; | — |
Countries
China
Contacts
Public ContactChen Wei
Yijishan Hospital affiliated to Wannan Medical College
Outcome results
None listed