sudden deafness with tinnitus
Conditions
Interventions
Group 1:Methylprednisolone
Group 2:Methylprednisolone+emocoagulase
Group 3:Methylprednisolone+ Sound therapy
Group 4:Methylprednisolone+Hemocoagulase+Sound therapy
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Aged 18~65 years old; 2) confirmed diagnosis of sudden hearing loss and tinnitus according to guidelines; 3) disease course of no longer than 3 weeks and haven't received any medical intervention; 4) willing to participate and sign consent form.
Exclusion criteria
Exclusion criteria: 1) presence of outer and middle ear disease(s); 2) presence of contraindication(s) to medicines involved in intervention strategies; 3) presence of severe hepatic, renal, cerebral or cardiovascular disease(s); 4) presence of psychiatric or any other disorder(s) compromising treatment or evaluation; 5) female with breast-feeding or possibility or confirmed pregnancy; 6) involved in any other clinical study during past 3 months; 7) unable or unwilling to cooperate during follow-ups.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pure tone threshold test;Tinnitus loudness and pitch;The tinnitus questionnaire scale;The tinnitus handicap inventory scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| tinnitus VAS scale;Beck Depression inventory,BDI;Beck Anxiety Inventory,BAI;the MOS item short from health survey, SF-36;Pittsburgh Sleep Quality Index,PSQI; | — |
Countries
China
Contacts
Public ContactYu Zhao
West China Hospital, Sichuan University
Outcome results
None listed