Contast-induced Acute Kidney Injury
Conditions
Interventions
Experimental group:Continuous intravenous infusion of furosemide was performed at 0.2-0.5mg/kg for 24 hours after coronary interventional procedures
control group:Continuous intravenous infusion of Normal saline was performed at 1-1.5ml/kg /h for 12 hours before operation and 24 hours after operation
Sponsors
Zhongda Hospital of Southeast University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Volunteered to participate in this trial and signed informed consent; (2) Aged =18 Years; (3) Planned coronary interventional procedures; (4) AGEF scores>1.48.
Exclusion criteria
Exclusion criteria: (1) Hypersensitivity to iodine-containing compounds or furosemide; (2) Lactation, pregnancy ; (3) Present or suspected acute kidney injury; (4) Use furosemide, contrast agent and renal toxicity drug within 1 week; (5) Severe renal insufficiency requiring hemodialysis; (6) Use IABP, acute heart failure, liver failure, connective tissue disease, tumor, severe infectious disease, cardiogenic shock in hospital, sudden cardiac death, etc.; (7) Has other related contraindications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of contrast-induced acute kidney injury; | — |
Secondary
| Measure | Time frame |
|---|---|
| Complications and adverse events related to intervention treatment: deterioration of renal function requiring dialysis (previously not required dialysis), severe electrolyte disturbance, acute pulmonary edema, length of hospital stay, deterioration of NYHA cardiac function grade above grade 1, malignant arrhythmia, readmission within ; | — |
Countries
China
Contacts
Public ContactChengchun Tang
Outcome results
None listed