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Efficacy of using premedication with reformulated simethicone emulsion during upper gastrointestinal endoscopy examination

Efficacy of using premedication with reformulated simethicone emulsion during upper gastrointestinal endoscopy examination:A multi-center, prospective, double-blinded, randomized controlled trial.

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900021689
Enrollment
Unknown
Registered
2019-03-05
Start date
2017-03-01
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

upper gastrointestinal disease

Interventions

A:patients received warm mixed solution contained 30ml NaHCO3 solution with a concentration of 5% and 15 ml reformulated simethicone emulsion (Berlin-Chemie AG, Berlin, Germany) 30 min before gastroen
B:patients received 45 ml 40 centigrade warm water 30 min before gastroendoscopy

Sponsors

Sir Run Run Shaw Hospital affiliated to Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. aged 18 to 75 years old; 2. patients who were arranged to undergo gastroendoscopy; 3. met ethical requirements and signed informed consent statement

Exclusion criteria

Exclusion criteria: 1. has upper gastrointestinal tract stricture and dysphagia; 2. has known allergy to the premedication; 3. is pregnant or breastfeeding; 4. has a history of upper gastrointestinal surgery; 5. has participated in other clinical studies within one month 6. has contraindication for gastroendoscopy.

Design outcomes

Primary

MeasureTime frame
Visibility scores;

Secondary

MeasureTime frame
Time required for gastroendoscopy examination;Flush times and volume of flush water during gastroendoscopy examination;

Countries

China

Contacts

Public ContactShujie Chen

Sir Run Run Shaw Hospital affiliated to Zhejiang University

chensj77@hotmail.com+86 13867489890

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 23, 2026