Rheumatoid arthritis
Conditions
Interventions
Case Series:IGU combined with MTX
Sponsors
Nanjing Drum Tower Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18 to 70 years, male or female; (2) Conform to 2010 ACR/EULAR RA Classification Standard (or 1987 ACR Standard) and over 6-month disease course; (3) The score of DAS 28 is over(including) 3.2; (4) Bone destruction can be seen in MRIX-ray or Color Doppler ultrasound of double hand; (5) Receive the treatment of IGU combined with MTX; (6) For those receiving NSAIDs or glucocorticoid treatment, their dose should remain unchanged for more than 2 weeks.
Exclusion criteria
Exclusion criteria: (1) Refuse to sign informed consent to participate in this trial; (2) With other serious disease requiring active treatment (cardiovascular diseases, respiratory diseases, endocrine diseases, digestive system diseases, nervous system diseases. hematological system diseases, mental illness and so on); (3) With other autoimmune diseases such as systemic lupus erythematosus, sjogren's syndrome and autoimmune liver disease; with other arthritis such as ankylosing spondylitis, psoriatic arthritis and gout. (4) With malignant tumor; (5) Be pregnancy or lactation; (6) With fatal complications such as severe infection; (7) Receive biologic DMARDs treatment; (8) Participate in other trials, and researchers think it may interfere this trail.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Joint evaluation; | — |
Secondary
| Measure | Time frame |
|---|---|
| MRI of double hand;X-ray of double hand;Pain assessment;Quality of Life Assessment; | — |
Countries
China
Contacts
Public ContactXuebing Feng
Nanjing Drum Tower Hospital
Outcome results
None listed