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Effect of Pirfenidone Capsule on urethral stricture recurrence after internal urethrotomy by cold knife

Effect of Pirfenidone Capsule on urethral stricture recurrence after internal urethrotomy by cold knife

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900021654
Enrollment
Unknown
Registered
2019-03-03
Start date
2019-03-02
Completion date
Unknown
Last updated
2019-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urethral Stricture

Interventions

experiment group:internal urethrotomy + pirfenidone capsule
control group:internal urethrotomy

Sponsors

Shanghai Jiaotong University Affiliated Sixth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Male adults, Diganosed as urethral stricture, stimate the urethral stricture length < 1.5 cm by the preoperative urinary tract imaging and Urethrocystoscope, sgined the informed consent.

Exclusion criteria

Exclusion criteria: 1. With a history of open urethral surgery or the urethra incision or urethra expansion history for many times; 2. With a history of severe hypertension; 3. With a history of diabetes; 4. With a history of the blood coagulation dysfunction or anticoagulant drugs; 5. With liver or kidney dysfunction; 6. Patients who can not cooperate with treatment; 7. Mental disorder or nerve dysfunction.

Design outcomes

Primary

MeasureTime frame
Urinary flow rate;Urethrography;

Secondary

MeasureTime frame
Routine uronoscopy;

Countries

China

Contacts

Public ContactZhang Xinru, Jihong Wang

Shanghai Jiaotong University Affiliated Sixth People's Hospital

wangjihongsh@aliyun.com+86 18930170242

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026