Compare the effects of airway local lidocaine anesthesia and airway physiological saline infiltration on perioperative respiratory adverse events in high-risk children: a randomized controlled trial

Topical airway lidocaine before endotracheal intubation in Children with a High Risk of Perioperative Respiratory Adverse Events: a randomized controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900021647

Enrollment

Unknown

Registered

2019-03-02

Start date

2019-03-01

Completion date

Unknown

Last updated

2019-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative Respiratory Adverse Events

Interventions

Lidocaine group:4 mg/kg of 2% lidocaine administered by spray over the supraglottic, glottis, and subglottic areas

control group:Normal saline

Eligibility

Sex/Gender

All

Age

0.5 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1. Aged 6 months to 12 years; 2. Anesthesia plan: general anesthesia endotracheal intubation; 3. =2 perioperative risk factors for respiratory complications; 4. ASA class I to II; 5. BMI 18-30.

Exclusion criteria

Exclusion criteria: 1. Heart and lung disease; 2. Liver and kidney dysfunction; 3. Neurological disease; 4. Airway or thoracic deformity; 5. Surgical site design respiratory; 6. Difficult intubation is expected; 7. Requirements or need preoperative use of sedatives; 8. Use postoperative analgesia pump; 9. Personal or familial history of allergies to local anesthetics; 10. Patients themselves or their guardians refused to attend the test or refuse to sign a consent form.

Design outcomes

Primary

Measure	Time frame
Perioperative Respiratory Adverse Events;	—

Secondary

Measure	Time frame
The incidence of sore throat and hoarseness within 24 hours after surgery;The incidence of aspiration within 24 hours after surgery;	—

Countries

China

Contacts

Public ContactGongjian Liu

Affiliated Hospital of Xuzhou Medical University

liugongjian61@hotmail.com+86 13952203528

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026