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Effects of perioperative oxygen fraction on postoperative pulmonary complication in pateints underwent neurosurgery: a randomized controlled trial

Effects of perioperative oxygen fraction on postoperative pulmonary complication in pateints underwent neurosurgery: a randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900021635
Enrollment
Unknown
Registered
2019-03-02
Start date
2019-04-01
Completion date
Unknown
Last updated
2020-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atelectasis

Interventions

Group 1:FiO2 0.6
Group 2:FiO2 0.3

Sponsors

Huadong Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Adult patients were aged 18 years or older, scheduled for brain surgery; 2. American Society of Anesthesiologists (ASA) physical status class I–III; 3. They could climb two flights of stairs without stopping, were considered clinically lung healthy; 4. Had an SpO2 of >= 94% when breathing air; 5. Body mass index (BMI, weight in kilograms divided by the square of the height in meters) of < 35 kg/m2; 6. The operative position is supine.

Exclusion criteria

Exclusion criteria: 1. Patients with chronic obstructive pulmonary disease, overt heart failure, obstructive sleep apnoea syndrome; 2. Patients with a difficult intubation or difficult mask ventilation was anticipated; 3. Chemotherapy within 3 months, and surgery within 30 days (except surgery under local anesthesia or dilation and curettage under general anesthesia); 4. Inability to give informed consent.

Design outcomes

Primary

MeasureTime frame
atelectasis;

Secondary

MeasureTime frame
aeration;PPCs;EVA;

Countries

China

Contacts

Public ContactWeidong Gu

Department of Anesthesiology, Huadong Hospital

mcwgwd@163.com+86 18918169021

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 8, 2026