Chronic Stable Coronary Disease
Conditions
Interventions
control group :Trimetazidine
Sponsors
Dongfang Hospital
Eligibility
Sex/Gender
All
Age
35 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Outpatient patients who meet the diagnostic criteria for chronic stable coronary heart disease: (1) Has a history of myocardial infarction, treated by or without revascularization (percutaneous coronary intervention or coronary artery bypass grafting); (2) Coronary angiography or coronary CT showed that the diameter of at least one main branch of the coronary artery is narrowed by more than 50%, and was treated with or without revascularization; 2. The type of TCM syndrome is Qi deficiency and blood stasis. 3. Patients aged 35-75 years; 4. Patients who volunteer to participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. History of myocardial infarction or unstable angina pectoris, or coronary revascularization (percutaneous coronary intervention or coronary artery bypass grafting) has occurred within the past 60 days; 2. Patients with one of the following diseases: (1) Hypertension patients who still have high blood pressure after antihypertensive treatment (systolic blood pressure =180 mmHg, diastolic blood pressure =100 mmHg); (2) Severe arrhythmia (atrial fibrillation with rapid ventricular response, atrial flutter, paroxysmal attack); (3) Pulmonary heart disease, rheumatic heart disease, myocarditis, cardiomyopathy, aortic dissection, pulmonary embolism; 3. hyperthyroidism, cervical spondylosis, biliary heart syndrome, gastroesophageal reflux disease or esophageal hiatus hernia, neurosis, climacteric syndrome and other diseases related chest pain symptoms; 4. serum alanine aminotransferase or serum creatinine > 2 times the upper limit of normal reference value; 5. Patients with severe hematological diseases; 6. malignant tumors; 7. pregnant women, lactating women or women of childbearing age with fertility requirements; 8. Patients with psychotic or cognitive impairment; 9. allergy to the test drug; 10. those who have participated in other clinical trials within one month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Electrocardiogram treadmill exercise test (metabolic equivalent); | — |
Secondary
| Measure | Time frame |
|---|---|
| ECG treadmill exercise test (duration of exercise test, depression time of exercise induced segment, positive condition of exercise test and maximum heart rate, maximum decrease of ST segment during exercise);Seattle Angina Scale;SF-36 QOL survey;TCM syndrome scores;Angina score;ECG; | — |
Countries
China
Contacts
Public ContactJinjin Lu
Dongfang Hospital
Outcome results
None listed