Cervical cancer
Conditions
Interventions
Sponsors
Zhujiang Hospital of Southern Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Female aged 18 to 75 years; 2. Local advanced cervical cancer patients diagnosed by pathology and FIGO stages; 3. ECOG PS 0-1; 4. At least one CR/MRI lesion can be measured; 5. Life expectancy = 3 months; 6. Peripheral blood images, liver and kidney functions are within the following permitted limits (tested within 7 days before the treatment); - Leukocyte(WBC) = 3.0×10^9/L or Neutrophil(ANC) = 1.5×10^9/L; - Hemoglobin (HGB) = 80g/L; - Platelet(PLT) = 100×10^9/L; - Liver transaminase (AST and ALT) < 3.0×ULN; - Total bilirubin(TBIL) < 1.5×ULN; - CREAT < 1.5×ULN. 7. Patients of child-bearing age must take effective birth control measures; 8. Sign the informed consent. Those who meet all of the criteria above will be included in the study.
Exclusion criteria
Exclusion criteria: 1. Have a history of other malignant tumors in the past 5 years, except for the cured basal cell carcinoma of the skin and carcinoma in situ of the cervix; 2. Those who are known to be allergic to the drug ingredients involved in the study; 3. Patients with a history of severe allergies or allergic constitution; 4. Pregnant or lactating women; 5. Patients with drug addiction, substance abuse, long-term alcohol abuse and AIDS; 6. Patients with cardiac failure or arrhythmia; Those who meet any of the criteria above will not be included in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| OS; | — |
Secondary
| Measure | Time frame |
|---|---|
| ORR;PFS;QOL; | — |
Countries
China
Contacts
Public ContactJian Zhang
Zhujiang Hospital of Southern Medical University
Outcome results
None listed