Pierre-Robin syndrome
Conditions
Interventions
The non-humidified group:The oxygen is not humidified with disposable bottle containing sterile water (Weigao, China)
The humidified group :The oxygen is humidified with disposable bottle containing sterile water (Weigao, China)
Sponsors
Children's Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
0.1 Years to 3 Years
Inclusion criteria
Inclusion criteria: (1) Children with Pierre-Robin syndrome who meet diagnostic criteria; (2) age less than 3 years old; (3) The children have undergone the surgery of mandibular traction; (4) Children received low-flow oxygen therapy (=5 ml/min) with nasal catheters; (5) No other congenital diseases such as congenital heart disease.
Exclusion criteria
Exclusion criteria: (1) The guardian does not agree to participate in the study and refuse to sign the informed consent; (2) The child has other diseases such as congenital diseases and respiratory infections; (3) Children received high flow (> 5 ml/min) heated and humidified oxygen therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average arterial oxygen partial pressure (PaO2);Average carbon dioxide partial pressure (PaCO2); | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of ventilator-associated pneumonia (VAP);Incidence of nasal cavity dryness;Incidence of nasal mucosal bleeding;Incidence of bacterial contamination of the humidified bottle;The cost of nasal oxygen therapy;Duration of ICU stay; | — |
Countries
China
Contacts
Public ContactZunjia Wen
Children's Hospital of Nanjing Medical University
Outcome results
None listed