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Cancer therapy and microbiota

An observational study on the changes in oral and gut microbiota following cancer therapy

Status
Active, not recruiting
Phases
Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900021581
Enrollment
Unknown
Registered
2019-02-28
Start date
2019-03-05
Completion date
Unknown
Last updated
2019-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Study on malignant tumour

Interventions

C:No anti-cancer therapy

Sponsors

Department of Microbiology, The Chinese University of Hong Kong
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Chinese people aged 18 or above, no upper age limit; 3. Having newly diagnosed malignant tumour; 4. A new case referred to the Oncology Centre for management.

Exclusion criteria

Exclusion criteria: 1. Patients who have previously received cancer therapy; 2. Patients who will receive concurrent radiotherapy; 3. Patients with conditions rendering them incapable to answer questionnaires or provide oral and stool samples; 4. Subjects who are unable to give consent.

Design outcomes

Primary

MeasureTime frame
Changes in gut and oral microbial community profiles measured by 16s and metagenomics sequencing before and after cancer therapy.;

Secondary

MeasureTime frame
Correlation of gut and oral microbial community profiles measured by 16s and metagenomics sequencing with respect to tumour type and toxicity.;

Countries

China

Contacts

Public ContactProf. Paul KS Chan

The Chinese University of Hong Kong

paulkschan@cuhk.edu.hk+852 35053339

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026