Hyperthyroidism
Conditions
Interventions
Chinese medicine group:Methimazole 15-20mg/d combined Chinese medicine Haizao Xiao-Yin Fang
Control group:Methimazole 15-20mg/d combined Chinese medicine placebo
Sponsors
Jiangsu Province Hospital of Integrated Traditional Chinese and Western Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-70 years old, with independent behavioral ability; 2. Accord with the diagnostic criteria for Graves disease, no medication, or previous history of GD, once treated with ATD, relapsed and reactivated drug therapy; 3. Conform to mild to moderate hyperthyroidism Performance (FT4 is within 3 times of the normal reference value); 4. Patients who meet the diagnostic criteria of TCM syndrome in TCM centers; 5. Patients who understand the full course of clinical studies and who have known consent.
Exclusion criteria
Exclusion criteria: 1. Include primary diseases such as cardiovascular, cerebrovascular, hepatic, renal and hematopoietic systems and psychosis; 2. Severe hyperthyroidism complications, complications such as liver damage, agranulocytosis, heart failure, etc.; 3. with thyroid gland Nodular patients; 4. allergies and multiple drug allergies; 5. pregnant or lactating women; 6. taking glucocorticoids or other drugs affecting thyroid function; 7. also receiving other clinically tested patients. Those who meet any of the above will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Thyroid function;Thyroid-related antibodies;Withdrawal rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM syndrome scores;Thyroid-related disease quality of life scale;Thyroid ultrasound;Urinary iodine;Heart rate;Weight;Recurrence rate; | — |
Countries
China
Contacts
Public ContactLiu Chao
Jiangsu Province Hospital of Integrated Traditional Chinese and Western Medicine
Outcome results
None listed