Study for Precise Intervention of Lipid Toxicity to Prevent and Cure Type 2 Diabetes Mellitus

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900021541

Enrollment

Unknown

Registered

2019-02-26

Start date

2019-04-01

Completion date

Unknown

Last updated

2019-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetes Mellitus

Interventions

Healthy control group:No intervention

Hypertriglyceridemia group:Low fat diet + Fenofibrate + ?-3 unsaturated fatty acids + Improve intestinal microecology with probiotics and prebiotics

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with hypertriglyceridemia

Exclusion criteria

Exclusion criteria: Patients with heart, liver and kidney dysfunction, cholelithiasis, gastrointestinal diseases and acute infections, pregnant breast-feeding, malignant tumors, etc.

Design outcomes

Primary

Measure	Time frame
Blood glucose;Blood lipid;Glycosylated hemoglobin;Blood insulin;Oral glucose tolerance test;Susceptible genes related to diabetes mellitus, hypertriglyceridemia and drug efficacy;Detection of microRNA related to diabetes mellitus, hypertriglyceridemia and drug efficacy;Intestinal flora;Lipid markers;	—

Countries

China

Contacts

Public ContactQingbo Guan

Shandong Provincial Hospital

qingboguan@126.com+86 15610119937

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026