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Retrospective Analysis of Multicenter Acute On Chonic Liver Failure (ACLF) Onset and Dynamic follow-up

Multicenter Acute On Chonic Liver Failure (ACLF) Onset and Dynamic follow-up Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900021539
Enrollment
Unknown
Registered
2019-02-26
Start date
2019-03-01
Completion date
Unknown
Last updated
2019-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute On Chonic Liver Failure

Interventions

Observation group:None

Sponsors

Tianjin Third Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients previously diagnosed or undiagnosed with chronic liver disease,under the acute insults ,patients manifested by jaundice (serum bilirubin=5mg/dL or 85µmol/L), coagulation disorders (INR=1.5 or prothrombin activity<40%), concurrent ascites and/or hepatic encephalopathy within 6 months (26 weeks,mostly 4 weeks)

Exclusion criteria

Exclusion criteria: 1. hepatocellular carcinoma or other malignant tumors; 2. Previously diagnosed with severe extrahepatic disease(such as chronic renal failure requires dialysis, severe cardiovascular and cerebrovascular diseases,severe chronic obstructive pulmonary disease and mental disease); 3. Concomitant with HIV infection;4.Concomitant with various other end-stage diseases.

Design outcomes

Primary

MeasureTime frame
CTP scoring criteria;MELD score;MELD- Na score;CLIF-SOFA score;CLIF - COF score;CLIF - CACLF score;—

Countries

China

Contacts

Public ContactTao Han

Tianjin Third Central Hospital

hantaomd@126.com+86 022-84112208

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Sep 11, 2026