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A Randomized Controlled Double-blind Clinical Study for Yiyang Pill on Cardiovascular Adverse Reactions caused by TSH inhibition treatment after Thyroid Cancer Operation

A Randomized Controlled Double-blind Clinical Study for Yiyang Pill on Cardiovascular Adverse Reactions caused by TSH inhibition treatment after Thyroid Cancer Operation

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900021523
Enrollment
Unknown
Registered
2019-02-25
Start date
2019-04-01
Completion date
Unknown
Last updated
2019-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

After thyroid cancer

Interventions

Experimental group:Oral Yiyang Pill
Blank Group:Oral Placebo

Sponsors

China-Japan Friendship Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) DTC was diagnosed by pathology after operation and aged less than 65 years; (2) TSH suppression therapy was performed routinely for more than one year after operation; (3) The TSH inhibitory target is below the normal level and belongs to subclinical hyperthyroidism; (4) Conscious symptoms such as panic and chest tightness, but resting heart rate is less than 90 times; (5) TCM syndrome is Qi and Yindeficiency; (6) Patients who have signed informed consent.

Exclusion criteria

Exclusion criteria: (1) Those who had cardiovascular abnormalities and diseases; (2) Patients with severe systemic and psychiatric diseases such as liver and kidney; (3) Anaphylaxis to the components contained in drugs; (4) Found distant metastases; (5) Pregnant and lactating women; (6) Those who are participating in other clinical drug trials; (7) Patients who do not sign the informed consent.

Design outcomes

Primary

MeasureTime frame
24 hour dynamic electrocardiogram;TSH;FT3;FT4;

Secondary

MeasureTime frame
Liver function;Renal function;Routine blood test;Blood pressure;

Countries

China

Contacts

Public ContactXia Zhongyuan

China-Japan Friendship Hospital

2718421708@qq.com+86 13701338757

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026