intrauterine adhesions,
Conditions
Interventions
Experimental group:PRF is fitted into the uterine cavity
Control group:Nothing is fitted into the uterine cavity
Sponsors
Beijing Shijitan Hospital, Capital Medical University
Eligibility
Sex/Gender
Female
Age
21 Years to 45 Years
Inclusion criteria
Inclusion criteria: (1) Women between the ages of 21 and 45 years; (2) The American Fertility Association's intrauterine adhesion severity rating standard (AFS) reaches Level II-III; (3) Signing informed consent.
Exclusion criteria
Exclusion criteria: (1) Chromosomes and genetic abnormalities; (2) Hematology and immunological diseases; (3) Hysteroscopy contraindications (acute inflammation of the genitourinary tract, religious beliefs, etc.); (4) History of cervical cancer; (5) History of previous pelvic radiation therapy; (6) There are other reproductive system diseases: abnormal uterine bleeding, endometriosis, polycystic ovary syndrome, premature ovarian failure or early onset ovarian insufficiency; (7) Treating endometrial diseases with sex hormones or other drugs within 3 months before treatment; (8) Participated in other clinical trials within 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in the degree of intrauterine adhesion before and after treatment (American Fertility Association AFS intrauterine adhesion severity rating standard); | — |
Secondary
| Measure | Time frame |
|---|---|
| Trends in menstrual model;Three-dimensional ultrasound observation of endometrial thickness and blood flow changes in late proliferative stage;General pathological structure of endometrial tissue before and after treatment, HE staining, Masson staining, etc.;Pregnancy rate; | — |
Countries
China
Contacts
Public ContactBai Wenpei
Beijing Shijitan Hospital, Capital Medical University
Outcome results
None listed