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Estrogen activates T-type Ca2+ channel in uterine telocytes and its mechanism in promoting uterine peristalsis

Estrogen activates T-type Ca2+ channel in uterine telocytes and its mechanism in promoting uterine peristalsis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900021497
Enrollment
Unknown
Registered
2019-02-23
Start date
2019-02-25
Completion date
Unknown
Last updated
2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uterine Peristalsis

Interventions

Intervention group 1:estrogen
Control group:None
Intervention group 2:Estrogen antagonist
Intervention group 3:Ca2+
control group:None
Intervention group 4:Ca2+ Blocking agent

Sponsors

The First Hospital Affiliated to Army Medical University (Southwest Hospital)
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 37 Years

Inclusion criteria

Inclusion criteria: 1. Premenopause women who will receive hysterectomy because of CIN or cervical carcinoma IA; 2. Women who will receive cesarean section because of proper surgical indication; 3. Aged 20 to 37 years.

Exclusion criteria

Exclusion criteria: 1. Patient who has multiple uterine leiomyomas; 2. Patient who has moderate or severe adenomyosis; 3. Patient with coagulation disorders; 4. Patient suffering from severe mental disorders, acute infection of the genitourinary system, or sexually transmitted diseases; 5. Patient with serious heart, liver, nephropathy, blood system disease; 6. Patient participating in other clinical studies or who have participated within a month.

Design outcomes

Primary

MeasureTime frame
Telocyte??;

Countries

China

Contacts

Public ContactLin Zhu

The First Hospital Affiliated to Army Medical University (Southwest Hospital)

zhulin19860218@hotmail.com+86 18502359625

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026