inflammatory bowel disease
Conditions
Interventions
AR group:Take 75mg of venlafaxine once daily in week 1
After one week, take venlafaxine 150mg once daily for nine months
Control group:Placebo
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) patients with other chronic or serious mental diseases, such as generalized anxiety disorder, psychosis, alcohol/drug dependence or cognitive impairment; 2) patients who are taking or have taken antipsychotic drugs or received psychological treatment within 3 months; 3) combine with other diseases that are highly correlated with depression/anxiety, such as cardiovascular disease, cancer and multiple sclerosis; 4) pregnancy, lactation, or pregnancy preparation; 5) patients taking any drug contraindicated with venlafaxine.
Exclusion criteria
Exclusion criteria: 1) patients with other chronic or serious mental diseases, such as generalized anxiety disorder, psychosis, alcohol/drug dependence or cognitive impairment; 2) patients who are taking or have taken antipsychotic drugs or received psychological treatment within 3 months; 3) combine with other diseases that are highly correlated with depression/anxiety, such as cardiovascular disease, cancer and multiple sclerosis; 4) pregnancy, lactation, or pregnancy preparation; 5) patients taking any drug contraindicated with venlafaxine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Harvey Bradshaw Index;CDAI;Modified Mayo scoring;HADS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammation Marker;WHOQoL;TNF-a, IL-6, IL-10;SES-CD;UCEIS;surgical rate;recurrent rate;Hormone efficiency/resistance; | — |
Countries
China
Contacts
Public ContactYan Zhang
West China Hospital, Sichuan University
Outcome results
None listed