Membranous Nephropathy
Conditions
Interventions
Treatment:Oral Mahuang Fuzi Soup and Shenzhuo Soup
Sponsors
Beijing Hospital of TCM
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1 Conforms to the IMN diagnostic criteria: The pathological light microscopy or electron microscopy has been used for the diagnosis of idiopathic membranous nephropathy (Wang Haiyan's "Nephrology" 3rd edition) or atypical membranous nephropathy. 2 Compliant with the diagnostic criteria of Chinese medicine Shaoyin Taiyin syndrome: (in combination with Feng Shilun's editor-edited "Interpretation of Zhang Zhongjing Medicine" standard): Main card: aversion to cold, cold hands and feet, back pain, edema, bloating, loose stools or dry stool, The tongue is tender, the moss is thin or watery, and the pulse is heavy. Second certificate: fatigue, shortness of breath, lazy words, spontaneous sweating, little urination, nocturia and so on. With the above three main certificates, sub-certificate 2 two, you can determine the Shaoyin Taiyin syndrome. 3 CKD1-3 patients (GFR>30ml/min).
Exclusion criteria
Exclusion criteria: 1 Progressive membranous nephropathy (degraded renal function; renal biopsy see necrotizing capillary vasculitis and >50% large crescent formation), accompanied by other kidney diseases such as IgA nephropathy, diabetic nephropathy; 2 Confirmed by hepatitis B, systemic lupus erythematosus, tumor, drug damage and other factors secondary and need to actively treat the primary disease, such as active hepatitis B and persistent liver function test transaminase abnormalities; or anti-nuclear antibodies, double Abnormal strand DNA, ANCA or other indicators of immune disease; 3 Patients with acute central nervous system diseases, severe gastrointestinal diseases, history of HIV infection, history of psychosis, history of malignant tumors; 4 Patients with other organs with serious diseases and dysfunctions, and with life-threatening complications such as severe infection; 5 Pregnant or lactating women; 6 Receiving other clinical trial researchers. Patients with any of the above conditions must be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-hour urine protein;Blood albumin; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM syndrome scores;Anti-PLA2 Antibody;Total Cholesterol;Triglyceride;Kidney Function Test; | — |
Countries
People Republic of China
Contacts
Public ContactLiu Baoli
Beijing Hospital of TCM
Outcome results
None listed