Traumatic brain injury
Conditions
Interventions
Group 1:Mosapride citrate was administered 8-12 hours before EN initiation
Group 2:Moxapride citrate was administered 24h after EN initiation
Sponsors
Army medical university
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. It meets the diagnostic criteria of the Branch of Neurological Injury and Repair of the Chinese Society of Neuroscience in 2016. It has a clear history of traumatic brain injury and has been confirmed by CT and/or MRI. 2. GCS score 3-12; 3. Before injury, there were no other visceral lesions, no nutritional, immune and metabolic diseases; 4. Aged 18-80 years old; 5. The risk assessment of enteral nutrition intolerance in severe patients was (>17); 6. Patients and their families volunteered to be the subjects of observation and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Enteral nutrition and/or treatment of gastrointestinal motility disorders have been initiated; 2. Complicated with severe thoracic and abdominal injuries; 3. Complicated with severe digestive tract diseases such as mechanical intestinal obstruction and gastrointestinal bleeding; 4. Pregnancy and maternity.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time for enteral nutrition to reach target energy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemoglobin;GLU;MTL; | — |
Countries
China
Contacts
Public ContactFang Yuli; Zhu Jingci
Army Medical University
Outcome results
None listed