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A cross-controlled trial for Zheng's multi-function devices to improve ventilation in patients with AECOPD type II respiratory failure

A cross-controlled trial for Zheng's multi-function devices to improve ventilation in patients with AECOPD type II respiratory failure

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900021424
Enrollment
Unknown
Registered
2019-02-21
Start date
2017-09-01
Completion date
Unknown
Last updated
2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute exacerbation of chronic obstructive pulmonary

Interventions

group 1:multifunction devices+PLB
group 2:PLB+multifunction devices

Sponsors

The First Affiliated Hospital of Guangzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
52 Years to 79 Years

Inclusion criteria

Inclusion criteria: (1) Aged 18-80 years, gender is not limited; (2) The subject has fully understood and voluntarily signed the informed consent form; (3) The results of pulmonary function tests in the past 1 year suggest that FEV1 / FVC < 70% and FEV1 < 80% predicted value, obstructive ventilatory dysfunction, which is subject to the final examination results; (4) Have a long history of smoking; (5) Can complete the corresponding respiratory rehabilitation training under the guidance.

Exclusion criteria

Exclusion criteria: (1) Patients who have undergone or are undergoing lung rehabilitation-related exercises in the past; (2) Excluding pneumothorax, pleural effusion, pulmonary embolism, bronchial asthma, tumor, unexplained fever, and large pulmonary bullae (>8cm); (3) Excluding severe primary diseases such as heart, liver, kidney, and hematopoietic system; (4) Excluding the back, chest and abdomen, or patients after surgery; (5) Continuous non-invasive ventilator assisted ventilation; (6) People with mental disorders, cognitive impairments, and inability to complete rehabilitation exercises; (7) Refusing to receive rehabilitation exercises and patients with poor compliance; (8) Patients considered by the investigator to be unsuitable for the study.

Design outcomes

Primary

MeasureTime frame
PetCO2;

Countries

China

Contacts

Public ContactZheng Zeguang

The First Affiliated Hospital of Guangzhou Medical University

zheng8620@139.com+86 18928868242

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026