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Clinical efficacy evaluation of clarithromycin in the treatment of chronic urticaria

Pharmacological action and mechanism of clarithromycin in the treatment of chronic urticaria

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900021411
Enrollment
Unknown
Registered
2019-02-20
Start date
2019-03-01
Completion date
Unknown
Last updated
2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic urticaria

Interventions

Control group:Normal treatment of using antihistamines
Experimental group:In addition to normal use of antihistamines, oral clarithromycin sustained-release tablets

Sponsors

Xi'an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged from 6 to 80 years; 2. Patients diagnosed with chronic urticaria (duration greater than or equal to 6 weeks); 3. Therapeutic effect was not obvious; 4. The blood parameters were normal and suitable for the patients taking clarithromycin; 5. Volunteer to participate in the program and be able to perform as required; 6. The informed consent has been signed and can be completed as required.

Exclusion criteria

Exclusion criteria: 1. The CU patients with other immune diseases; 2. Patients with definite indications of h. pylori infection and other microbial disturbances; 3. Patients with history of chronic bacterial or fungal infections; 4. Patients have been diagnosed with physical urticaria (including artificial urticaria), cholinergic urticaria or urticaria vasculitis; 5. Patients are unable to cooperate or adhere to treatment and have poor predictive compliance; 6. Pregnant and nursing women; 7. The patients are also participating in other clinical trials.

Design outcomes

Primary

MeasureTime frame
effective rate;inhibition ratio;

Countries

China

Contacts

Public ContactLangchong He

Xi'an Jiaotong University

helc@mail.xjtu.edu.cn+86 029 82655392

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026