Small Doses of Butorphanol prevents sufentanil-induced cough during general anesthesia induction: A randomized controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900021404

Enrollment

Unknown

Registered

2019-02-19

Start date

2019-03-01

Completion date

Unknown

Last updated

2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Opioid-induced cough

Interventions

1:butorphanol 0.1mg IV

2:butorphanol 1mg IV

3:normal saline IV

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists (ASA) physical status I–II patients, aged 18~65 years, and weighed 45~80kg.

Exclusion criteria

Exclusion criteria: Exclusion criteria included a history of smoking, asthma, chronic cough, pregnancy, upper airway infection within 2 weeks of surgery, bronchodilators, or steroids in the previous 2 weeks.

Design outcomes

Primary

Measure	Time frame
Incidence of cough;Severity of cough;SBP;DBP;HR;	—

Countries

China

Contacts

Public ContactTiejun Zhang

Hospital of Stomatology, Wuhan University

ztj@whu.edu.cn+86 13307105227

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026