chronic kidney diseases
Conditions
Interventions
Sponsors
The Second Affiliated Hospital of the Amy Medical University
Eligibility
Sex/Gender
All
Age
14 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. renal impairment 3 months, with or without decreased glomerular filtration rate (GFR). Renal damage refers to the abnormal structure or function of the kidney, manifested as one of the following: 1) pathological examination abnormalities; 2) eGFR<60ml/min/1.73m2 3 months, with or without renal damage.EGFR =169 Scr-0.608 CysC-0.63 Age-0.157 (0.83 if female); 2. For patients with CKD stage 3-5 (non-dialysis), age 14-65 years old (including 14 and 65 years old), gender, ethnicity is not limited; 3. The ultrasound of the cervical blood vessels showed no cervical vascular plaque and no atherosclerosis. 4. patients signed informed consent.
Exclusion criteria
Exclusion criteria: 1. unable or unwilling to complete the required process for the research; 2. participating in other interventional clinical trials; 3. women who are pregnant or lactating; 4. previous diagnosis of CKD with cardiovascular disease or previous cardiovascular disease patients, it shall clearly diagnosis myocardial infarction, heart failure, cerebral hemorrhage and other serious cardiovascular and cerebrovascular complications; 5. NYHA level III or IV heart failure, that is, there is a basic heart disease, physical activity was significantly limited, less than the general physical activity or rest state may appear fatigue, palpitations, asthma or angina symptoms; 6. Lilitide cirrhosis; 7. Therefore HIV infection or AIDS; 8. In the past 2 years due to malignant tumor chemotherapy or alkylation agent treatment; 9. kidney transplant patients; 10. on the existence of deep venous thromboembolism before inclusion; 11. In the prior to entering the group, in the long-term use of aspirin or hydroclopidogrel, or in the recent three months in the short use of aspirin or hydroclopidogrel; 12. the patients with active bleeding or coagulation dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Atherosclerosis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Complex cardiovascular events;all-cause mortality;A 50% drop in eGFR; | — |
Countries
China
Contacts
Public ContactZhao Jinghong
The Second Affiliated Hospital of the Amy Medical University
Outcome results
None listed