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Strategies for optimizing antimicrobial therapy in children with severe Gram-positive cocci infection

Strategies for optimizing antimicrobial therapy in children with severe Gram-positive cocci infection

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900021386
Enrollment
Unknown
Registered
2019-02-18
Start date
2018-01-01
Completion date
Unknown
Last updated
2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infection disease

Interventions

Study group:PPK/PD model
control gruop:none

Sponsors

Beijing Children's Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged 28 days to 18 years; 2. Comply with the income conditions of the Department of Critical Care Medicine (including PICU and CCU) of Beijing Children's Hospital, diagnosed or diagnosed as severe Gram-positive (G+) cocci infection; 3. vancomycin or linezolid intravenous treatment > 3d; 4. pediatric critical cases score <90 points, or meet the US PICU occupancy criteria.

Exclusion criteria

Exclusion criteria: 1. unable to obtain a blood sample; 2. lack of biochemical indicators such as liver and kidney function during the medication.

Design outcomes

Primary

MeasureTime frame
Clinical efficacy;adverse drug reaction;—

Countries

China

Contacts

Public ContactQian Suyun

Beijing Children's Hospital

syqian1211@163.com+86 010 59616767

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 24, 2026