Breast cancer
Conditions
Interventions
Case series:implantation radiotherapy
Sponsors
the Affiliated Hospital of Southwest Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Pathologically confirmed early breast cancer patients (T1-2N0M0): (1) patients with absolute surgical contraindications; (2) patients who refuse surgical treatment; 2. Aged 18 years or above; 3. No contraindication of radiotherapy. The survival time is expected to be greater than 6 months; 4. ZPS score 0-2 points; 5. HCG of urine and serum was negative in 72 hours before treatment; 6. Bone marrow function is normal, as follows: white blood cell count > 3.5 *109/L, hemoglobin > 90 g/L (without blood transfusion), neutrophil count (> 2.0 *109/L), platelet count (> 100 *109/L), serum creatinine clearance rate (> 60 ml/min), ALT, AST < 2.5 times normal reference value. Bilirubin is within normal limits; 7. Coagulation function was normal: PT 12-16s, INR 0.8-1.5, APTT 24-36s, FIB2-4g/L. Pre-transfusion tests: HIV and TP were negative (-); 8. No allergic history of narcotics, such as lidocaine; 9. informed consent and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. There is a history of serious cardiovascular diseases, such as uncontrolled hypertension, unstable angina, congestive heart failure, acute myocardial infarction, and transmural myocardial infarction within 6 months; 2. Combined with uncontrolled neuropathy (grade 2 or above) or psychotic patients; 3. Systemic distant metastasis was not effectively controlled; 4. Patients with acute bacterial or fungal infections need intravenous anti infective treatment; 5. Liver dysfunction causes jaundice or coagulopathy; 6. Pregnant or child-bearing age women refuse to adopt appropriate contraceptive measures.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Breast mass;Breast mass; | — |
Countries
China
Contacts
Public ContactYang HongRu
Oncology Department, the Affiliated Hospital of Southwest Medical University
Outcome results
None listed