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Dynamic facial changes in patients with acromegaly before and after surgery: Prospective controlled study based on 3D Facial Analysis

Dynamic facial changes in patients with acromegaly before and after surgery: Prospective controlled study based on 3D Facial Analysis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900021359
Enrollment
Unknown
Registered
2019-02-17
Start date
2019-02-28
Completion date
Unknown
Last updated
2019-02-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acromegaly

Interventions

acromegaly group versus normal people:NA

Sponsors

Chinese Academy of Medical Sciences Peking Union Medical College Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) typical presentations of acromegaly; (2) GH and IGF-1 levels in accordance with the endocrine diagnostic criteria; (3) a finding of a pituitary adenoma on contrast-enhanced MRI; (4) adult patients (>18 years) with no gender restriction; (5) other pituitary related hormones, including prolactin, follicle-stimulating hormone, luteinizing hormone, adrenocorticotropic hormone, cortisol, and thyroid stimulating hormone, within the normal range to avoid potential effects on the facial structures

Exclusion criteria

Exclusion criteria: 1. other diseases that change the face, such as Cushing, hypothyroidism, hyperthyroidism, trauma, etc.; 2. mental illness and high intelligence damage that cannot be combined with photography; 3. malignant tumor, in short survival.

Design outcomes

Primary

MeasureTime frame
3D facial photo;

Secondary

MeasureTime frame
hormone level;

Countries

China

Contacts

Public ContactXiao Long

Chinese Academy of Medical Sciences Peking Union Medical College Hospital

pumchlongxiao@163.com+86 13810193175

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026