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Do endometrial leucocytes and angiogenesis in the peri-implantation period predict hypertensive disorders in the subsequent pregnancy?

Do endometrial leucocytes and angiogenesis in the peri-implantation period predict hypertensive disorders in the subsequent pregnancy?

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900021350
Enrollment
Unknown
Registered
2019-02-16
Start date
2019-04-01
Completion date
Unknown
Last updated
2020-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertensive disorders of pregnancy

Interventions

Case series:Nil

Sponsors

Department of Obstetrics and Gynaecology, Prince of Wales Hospital, Chinese University of Hong Kong
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Women with a history of reproductive failure, including infertility, recurrent implantation failure and recurrent miscarriage; 2. Women younger than 40 years old.

Exclusion criteria

Exclusion criteria: 1. Women who have any uterine anomaly (such as fibroid and adenomyosis) or intrauterine pathology (such as polyp and intrauterine adhesion); 2. Hydrosalpinx; 3. Women diagnosed as hypertension prior to the endometrial biopsy; 4. On aspirin or steroid treatment; 5. Diabetes.

Design outcomes

Primary

MeasureTime frame
Immunohistochemistry staining;—

Countries

China

Contacts

Public ContactChen Xiaoyan

Department of Obstetrics and Gynaecology, Prince of Wales Hospital, Chinese University of Hong Kong

chenxiaoyan@cuhk.edu.hk+852 35051764

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026