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A comparative study for the effects of different nerve block methods on patient-controlled intravenous analgesia after knee replacement

A comparative study for the effects of different nerve block methods on patient-controlled intravenous analgesia after kneereplacement

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900021349
Enrollment
Unknown
Registered
2019-02-16
Start date
2019-02-14
Completion date
Unknown
Last updated
2019-02-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Total Knee Replacement

Interventions

A:Injection of mixed drugs around knee joint
B:Femoral Nerve Block and Injection of Mixed Drugs around Knee Joint
C:Femoral Nerve Block and Injection of Mixed Drugs around Knee Joint

Sponsors

Beijing Chaoyang Hospital Affiliated to Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. American Society of Anesthesiologists Classification I-II; 2. Those who meet the diagnostic criteria of knee osteoarthritis and have no valgus deformity of knee joint; 3. Initial unilateral TKA without history of knee surgery; 4. Aged 50 to 75 years; 5. Normal liver and kidney function; 6. It can cooperate with the operation of examination and treatment.

Exclusion criteria

Exclusion criteria: 1 Unilateral TKA combined with removal of other implants; 2 A drug in a previously defined allergic or intolerant analgesic regimen; 3 Rheumatoid arthritis and other inflammatory diseases; 4 Knee joint infection or suspicious infection; 5 Complicated with coagulation dysfunction; 6 Preoperative history of chronic pain, puncture site infection, anticoagulation therapy, allergic reaction to local anesthesia, body mass index > 28, etc.

Design outcomes

Primary

MeasureTime frame
VAS;

Secondary

MeasureTime frame
hemodynamic monitoring;Record the number of PCIA pressing, the total amount of infusion and the amount of flurbiprofen ester given after operation at 24h and 48h.;

Countries

China

Contacts

Public ContactWang Yun

Department of Anesthesiology, Beijing Chaoyang Hospital

wangyun129@ccmu.com.cn+86 13521611825

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026