Total Knee Replacement
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. American Society of Anesthesiologists Classification I-II; 2. Those who meet the diagnostic criteria of knee osteoarthritis and have no valgus deformity of knee joint; 3. Initial unilateral TKA without history of knee surgery; 4. Aged 50 to 75 years; 5. Normal liver and kidney function; 6. It can cooperate with the operation of examination and treatment.
Exclusion criteria
Exclusion criteria: 1 Unilateral TKA combined with removal of other implants; 2 A drug in a previously defined allergic or intolerant analgesic regimen; 3 Rheumatoid arthritis and other inflammatory diseases; 4 Knee joint infection or suspicious infection; 5 Complicated with coagulation dysfunction; 6 Preoperative history of chronic pain, puncture site infection, anticoagulation therapy, allergic reaction to local anesthesia, body mass index > 28, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| hemodynamic monitoring;Record the number of PCIA pressing, the total amount of infusion and the amount of flurbiprofen ester given after operation at 24h and 48h.; | — |
Countries
China
Contacts
Department of Anesthesiology, Beijing Chaoyang Hospital