Skip to content

Laparoscopic versus Open Liver Resection for Large Hepatocellular Carcinoma (5-10cm): A Prospective Randomized Controlled Study

Laparoscopic versus Open Liver Resection for Large Hepatocellular Carcinoma (5-10cm): A Prospective Randomized Controlled Study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900021310
Enrollment
Unknown
Registered
2019-02-13
Start date
2019-02-18
Completion date
Unknown
Last updated
2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular carcinoma

Interventions

Laparoscopic liver resection group :Laparoscopic liver
Open liver resection group :Open liver resection

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Elective liver resection; 2. Agree to sign the informed consents; 3. Presentation of hepatocellular carcinoma (HCC, 5-10cm) with contrast-enhanced ultrasound, CT, or/and MRI; 4. Child-pugh A; 5. Without the presentation of extrahepatic metastasis, or tumor thrombus in portal vein or other major vascular; 6. Male or female patients aged 18 to 75years.

Exclusion criteria

Exclusion criteria: 1. Liver resection combined with other abdominal organ resection except for gallbladder (such as radiofrequency ablation, splenectomy, and pancreatectomy so on); 2. Reconstruction of bile duct, portal vein or other major vascular were performed in liver resection procedure; 3. Repeated liver resection; 4. Histories of major upper abdominal surgery.

Design outcomes

Primary

MeasureTime frame
Disease-free survival;Overall survival;Intraoperative blood loss;R0 resection rates;Early mortality;Postoperative overall complication rates;

Secondary

MeasureTime frame
Operation time;Postoperative stay;wound infection;respiratory infection;ascites;bile leakage;liver failure;

Countries

China

Contacts

Public ContactYonggang Wei

Department of Liver Surgery, Center of Liver Transplantation, West China Hospital of Sichuan University

yourwyg@163.com+86 18980602268

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026