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Randomized double-blind controlled trial for comparison of phenylephrine and norepinephrine for management of post-spinal hypotension in twin pregnancy

Randomized double-blind controlled trial for comparison of phenylephrine and norepinephrine for management of post-spinal hypotension in twin pregnancy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900021281
Enrollment
Unknown
Registered
2019-02-11
Start date
2019-02-18
Completion date
Unknown
Last updated
2019-02-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotension after spinal anesthesia

Interventions

Sponsors

West China Second Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Pregnant women with twin pregnancy between 37 to 42 weeks of gestation, aged greater than 20 years, ASA class I- II, weighing less than 100kg, height between 150 and 180 cm undergoing elective cesarean delivery under spinal-epidural anesthesia will be enrolled in this study

Exclusion criteria

Exclusion criteria: Inability to receive spinal anesthesia, allergy to phenylephrine or norepinephrine, hypertensive disorders (pregnancy-induced hypertension, chronic hypertension, or preeclampsia), diabetes mellitus, hypermetabolic states (e.g. thyroid disease), cerebrovascular or cardiovascular diseases, inability or refusal to give inform

Design outcomes

Primary

MeasureTime frame
Cardiac output;blood pressure;

Secondary

MeasureTime frame
Heart rate;Maternal complications;Apgar score;Umbilical arterial blood gas analysis;Umbilical vein blood gas analysis;

Countries

China

Contacts

Public ContactZhou Jieshu

West China Second Hospital, Sichuan University

jieshuzhou@foxmail.com+86 15008285449

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026