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Genomics and metabolomic approach studying the diversity of gut microbiota in patients with psoriasis

Genomics and metabolomic approach studying the diversity of gut microbiota in patients with psoriasis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900021264
Enrollment
Unknown
Registered
2019-02-05
Start date
2019-06-01
Completion date
Unknown
Last updated
2019-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psoriasis

Interventions

Control group:No intervention

Sponsors

People’s Hospital of Xinjiang Uygur Autonomous Region
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Case group: According to Zhao Bian's "Clinical Skin Disease 2010 Edition", patients with typical psoriasis (laser scanning confocal microscopy or / and dermatological pathology to assist diagnosis), requiring PASI score = 6 points, 3 months No immunosuppressive drugs, such as systemic corticosteroids, methotrexate, cyclosporine or anti-tumor necrosis factor alpha, have not been orally administered to the intestinal flora within 3 months, and no systemic antibiotics have been used within 2 weeks. No cirrhosis, intestinal diseases and bacterial infections. In the control group, the healthy family members with similar living conditions in the patient group were selected, and the spouses who lived together for more than 1 year or the siblings with the same age and gender were 1:1 matched with the psoriasis vulgaris patients group, that is, each group of experimental samples included: A patient with psoriasis vulgaris and a matched healthy control.

Exclusion criteria

Exclusion criteria: Exclude people with autoimmune diseases, tumors or hereditary diseases.

Design outcomes

Primary

MeasureTime frame
Genomics;Metabolomics;

Countries

China

Contacts

Public ContactXiaojing Kang
drkxj666@163.com+86 13999927999

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026