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Autologous retinal transplantation combined with RPE for the treatment of extreme highly myopic macular hole retinal detachment: A Randomized Controlled Study

Autologous retinal transplantation combined with RPE for the treatment of extreme highly myopic macular hole retinal detachment: A Randomized Controlled Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900021258
Enrollment
Unknown
Registered
2019-02-03
Start date
2019-06-01
Completion date
Unknown
Last updated
2019-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

high myopic macular hole retinal detachment

Interventions

Group 1:ILM peeling with autologous retinal transplantation combined with RPE
Group 2:ILM peeling with autologous retinal transplantation
Group 3:ILM peeling

Sponsors

The Eye Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) high myopic MHRD eyes without history of vitrctomy; (2) high myopia (diopter >-6.0D, axial length>26mm);Myopic macular lesions (classification 3+CNV or Fuchs plaque, classification 4); The presence of posterior staphyloma; (3) no obvious vitreous retinal hyperplasia (PVR grade A-B); (4) aged at least 18 years old; (5) be able and willing to participate in clinical trials

Exclusion criteria

Exclusion criteria: (1) retinal detachment caused by idiopathic macular hole or traumatic macular hole; (2) retinal detachment combined with other retinal holes; (3) macular hole retinal detachment combined with choroidal detachment; (4) obvious vitreous retinal hyperplasia (PVR grade C); (5) history of scleral reinforcement; (6) not expected to follow in the clinical trial center; (7) those with neurological or mental diseases that cannot cooperate with the examination; (8) the informed consent cannot be obtained.

Design outcomes

Primary

MeasureTime frame
Macular hole closure rate ;retinal reattachment rate ;best corrected visual acuity ;

Countries

China

Contacts

Public ContactYong Wei

The Eye Hospital of Wenzhou Medical University

weiyongdoctor@163.com+86 15057551266

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026