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Clinical study for diabetic keratopathy and its correlation with retinal RNFL

Clinical study for diabetic keratopathy and its correlation with retinal RNFL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900021243
Enrollment
Unknown
Registered
2019-02-03
Start date
2019-07-01
Completion date
Unknown
Last updated
2019-02-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic keratopathy

Interventions

Diabetes without eye disease group:Measurement of Corneal and Retinopathy Related Indicators
Non-proliferative diabetic retinopathy group:Measurement of Corneal and Retinopathy Related Indicators
Proliferative diabetic retinopathy group:Measurement of Corneal and Retinopathy Related Indicators
Normal control group:Measurement of Corneal and Retinopathy Related Indicators

Sponsors

Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with diabetes; 2. Aged 18 to 90 years, male or female; 3. The communication is accessible and does not affect the assessment.

Exclusion criteria

Exclusion criteria: 1. Patients with corneal ulcer, corneal endothelial decompensation or other corneal diseases; 2. Vitreous hemorrhage and retinal detachment; 3. Refractive interstitial opacity (such as severe cataract) affects fundus observers; 4. Ophthalmological surgeons in 3 months; 5. Suffering from serious cardiovascular and cerebrovascular diseases; 6. Sudden other acute diseases; 7. Can not self-evaluators; 8. Participate in other drug testers; 9. Researchers believe there are other reasons not suitable for clinical trials.

Design outcomes

Primary

MeasureTime frame
Corneal nerve fibers;Retinal nerve fiber layer thickness (RNFL);

Secondary

MeasureTime frame
Number of corneal endothelial cells;Meibomian gland secretory function;BUT;Dry Eye Symptom;Tear secretion;

Countries

China

Contacts

Public ContactGuo Jianxin

Affiliated Hospital of Xuzhou Medical University

Guojianxin_724@126.com+86 0516 85806276

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026