Diabetic keratopathy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with diabetes; 2. Aged 18 to 90 years, male or female; 3. The communication is accessible and does not affect the assessment.
Exclusion criteria
Exclusion criteria: 1. Patients with corneal ulcer, corneal endothelial decompensation or other corneal diseases; 2. Vitreous hemorrhage and retinal detachment; 3. Refractive interstitial opacity (such as severe cataract) affects fundus observers; 4. Ophthalmological surgeons in 3 months; 5. Suffering from serious cardiovascular and cerebrovascular diseases; 6. Sudden other acute diseases; 7. Can not self-evaluators; 8. Participate in other drug testers; 9. Researchers believe there are other reasons not suitable for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Corneal nerve fibers;Retinal nerve fiber layer thickness (RNFL); | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of corneal endothelial cells;Meibomian gland secretory function;BUT;Dry Eye Symptom;Tear secretion; | — |
Countries
China
Contacts
Affiliated Hospital of Xuzhou Medical University