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Clinical study for penetrating keratoplasty combined with anterior vitrectomy to prevent positive vitreous pressure

Clinical study for penetrating keratoplasty combined with anterior vitrectomy to prevent positive vitreous pressure

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900021227
Enrollment
Unknown
Registered
2019-02-02
Start date
2016-04-18
Completion date
Unknown
Last updated
2019-02-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

full-thickness cornea disease

Interventions

Experimental group:penetrating keratoplasty combined with stepwise anterior vitrectomy
Control group:penetrating keratoplasty

Sponsors

Department of Ophthalmology, Tongji Hospital Affiliated with Tongji University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
28 Years to 65 Years

Inclusion criteria

Inclusion criteria: patients with full-thickness or deep corneal disease that had led to corneal opacities that impair vision, such as corneal leucoma with or without IOL implantation, chronic bullous keratopathy, and acute corneal hydrops caused by keratoconus.

Exclusion criteria

Exclusion criteria: patients with a history of vitrectomy, vitreoretinopathy, active infectious keratitis, uncontrolled intraocular pressure, as well as patients with severe systemic disease who could not tolerate surgery.

Design outcomes

Primary

MeasureTime frame
BCVA;central corneal thickness;duration of vitrectomy;imes of the stepwise vitrectomy;duration of vitrectomy;the anterior chamber width;crystalline lens rise;intraocular pressure;

Countries

China

Contacts

Public ContactYanlong Bi

Department of Ophthalmology, Tongji Hospital Affiliated with Tongji University School of Medicine

biyanlong@tongji.edu.cn+86 13816261568

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 20, 2026