Hypoproteinemia
Conditions
Interventions
Case series:Teicoplanin
Sponsors
The Affiliated Hospital of Putian University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Spesis patients who are treated with teicoplanin; 2. aged 18 years, male or female; 3. Meet the sepsis diagnose standard of The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3); 4. Patitents who are diagnosed by the clinician with Gram-positive cocci include one of the following respiratory infections, bloodstream infection, catheter-related infection, infective endocarditis, neutropenia, fever, bone and joint infection, abdominal infection, skin and soft tissue; 5. The presence of hypoproteinemia during the course of administration (serum albumin<25g/L).
Exclusion criteria
Exclusion criteria: 1. Patients who had teicoplanin Allergy or Allergy history; 2. Patients who used teicoplanin for prevention; 3. Patients who refused to participate the study, or who were unable to obtain blood samples due to unwillingness of the patient and the family of the patient; 4. Unacceptable adverse reactions or serious adverse events; 5. Patients were dead within 24 hours with the treatment of teicoplanin; 6. Patients with hypoproteinemia who were corrected before using teicoplanin.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Trough concentrations;Albumin;APACHE II Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical diagnosis;leukocyte;Procalcitonin;C-reactive protein;Body Temperature;Age;Gender;Height;Weight; | — |
Countries
China
Contacts
Public ContactQi Lin
The Affiliated Hospital of Putian University
Outcome results
None listed