esophageal and intragastric pressure
Conditions
Interventions
Group 1:Intravenous Fentanyl
Group 2:Intravenous butorphanol
Sponsors
Third Affiliated Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Volunteers aged 18-40 years old were fasting for 6 hours before the test; 2. Agree to volunteer to participate in the study; 3. good health, no combined digestive tract and cardiovascular disease, no liver and kidney dysfunction.
Exclusion criteria
Exclusion criteria: Obesity with body mass index over 30 kg / m2, pregnancy, drug abuse or alcohol abuse, multiple heartburns per week, history of gastroesophageal reflux or any history of esophageal or gastric surgery. Volunteers take medications that may alter the pressure of the gastroesophageal sphincter, including anticholinergics (including atropine, Glon), dopamine and derivatives, sodium nitroprusside, ganglion blockers, antihistamines, corticosteroids, topical Nicotine, tricyclic antidepressants, beta adrenergic stimulants, opioids and oral contraceptives.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| esophageal and intragastric pressure; | — |
Countries
China
Contacts
Public ContactCHENG NAN
Third Affiliated Hospital, Sun Yat-sen Universit
Outcome results
None listed