Depression
Conditions
Interventions
Group 1:YUEJU PILL 12g/day+placebo
Group 2:YUEJU PILL 23g/day(week1)12g/day(week2-4)+placebo
Group 3:ESCITALOPRAM 10mg/day+placebo
Sponsors
The Fourth People's Hospital of Taizhou
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Meet the diagnostic criteria for DSM-V depression; 2) Aged 18-75 years old; 3) Hamilton Depression Scale (24 items) score HAMD-24 = 20 points; Montgomery Depression Rating Scale score MADRS = 12 points; 4) Chinese medicine (including Chinese herbal medicines and medicinal herbs and decoctions), Western medicine (Prozac, Lai Shi Pu, Bolexin, etc.) have not been used in the past 1 week, or in the short term (3-5) Those who have taken the above drugs within days) have been deactivated for more than 7 days; 5) Those who are willing to accept 30 days of treatment, informed consent, and signed informed consent.
Exclusion criteria
Exclusion criteria: 1) Patients with suicidal depression, the third score of the Hamilton Depression Scale = 2 points; 2) Those who are suffering from other mental illnesses other than depression, as well as those caused by external environmental disturbances or traumatic brain injury; 3) pregnant or lactating women; 4) Those with a history of drug allergy; 5) Patients with severe primary diseases such as cardiovascular, pulmonary, liver and kidney and hematopoietic system, and severe brain organic diseases and mental illnesses; 6) Alcohol and/or psychoactive substances, drug abusers and dependents (including sleeping pills); 7) Those who do not meet the inclusion criteria, do not use the drugs according to the regulations, can not judge the efficacy or safety of the data and other factors affecting the efficacy and safety. 8) Those who cannot understand the scale content due to lack of consciousness, language barrier, intelligence and cultural level.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HAMD-24;QIDS-16;PHQ-9;Stagnation syndrome TCM syndrome differentiation scale;TCM constitution classification and judgment self test; | — |
Countries
China
Contacts
Public ContactCHEN GANG
Nanjing University of Traditional Chinese Medicine
Outcome results
None listed