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Effect of pretreatment with oxycodone hydrochloride on opioid-induced cough during induction of general anesthesia: a randomized controlled trial

Treatment of cough caused by opioids during induction of general anesthesia: a randomized controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900021087
Enrollment
Unknown
Registered
2019-01-28
Start date
2019-05-01
Completion date
Unknown
Last updated
2019-02-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cough

Interventions

Group 1:2 ml of normal saline was given to the patient before general anesthesia induction
Group 2:Intravenous injection of oxycodone hydrochloride 0.1mg/Kg before general anesthesia induction
Group 3:Intravenous injection of oxycodone hydrochloride 0.2mg/Kg before general anesthesia induction
Group 4:Intravenous injection of oxycodone hydrochloride 0.3mg/Kg before general anesthesia induction

Sponsors

Department of Anesthesiology, Second Affiliated Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective surgery under general anesthesia; 2. ASA I- II; 3. Aged 18 to 80 years.

Exclusion criteria

Exclusion criteria: Not stated

Design outcomes

Primary

MeasureTime frame
cough;—

Secondary

MeasureTime frame
Blood Pressure;Heart Rate;—

Countries

China

Contacts

Public ContactYong He

The Second Affiliated Hospital of Nanjing Medical University

710853013@qq.com+86 17705170658

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026