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Optical Coherence Tomography Angiography Peripapillary and Macular Vascular Density Measurements and the Visual Field in Acute Primary Angle Closure Glaucoma

Optical Coherence Tomography Angiography Peripapillary and Macular Vascular Density Measurements and the Visual Field in Acute Primary Angle Closure Glaucoma

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900021086
Enrollment
Unknown
Registered
2019-01-28
Start date
2019-01-25
Completion date
Unknown
Last updated
2019-02-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Interventions

PACG1:the duration of high IOP less than 24 hours
PACG2:the duration of high IOP less than one week and more than 24 hours
PACG3:the duration of high IOP more than one month
PACS:nothing
ARC:Age-related cataract

Sponsors

Tianjin Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Only one eye of each patient has a history of acute angle-closure attack,while the other eye was unaffected; 2. Acute angle-closure attack,defined by the presence of at least 2 symptoms (such as ocular pain and nausea /vomiting), increased IOP greater than 21 mm mercury column, and at least 3 findings from the clinical examination (for example,corneal edema,peripheral anterior chamber depth equal to or less than one quarter of the peripheral corneal thickness,gonioscopic examination of angle closure,etc.); 3. The unaffected eye had no symptoms or signs of acute angle-closure attack, glaucomatous optic neuropathy, or reproducible visual field loss.

Exclusion criteria

Exclusion criteria: 1. High myopia or high hyperopia (mean diopter =±6D); 2. Chronic retinopathy,non-glaucomatous optic neuropathy,history of uveitis,history of ocular trauma and eye diseases that affect the opacity of ocular refractive media; 3. Previous history of eye surgery (except for fully recovered cataract surgery); 4. Patients with not well-controlled hypertension and diabetes.

Design outcomes

Primary

MeasureTime frame
macular vessel density;Peripapillary vessel density;visual field;

Secondary

MeasureTime frame
foveal avascular zone;

Countries

People's Republic of China

Contacts

Public ContactJin Yang

Tianjin Eye Hospital

yangjin979@163.com+86 27313336-81000

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026