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Effects of different levels of end-expiratory positive pressure on pulmonary dynamic compliance and alveolar-arterial oxygen partial pressure difference in patients undergoing gynecological laparoscopic surgery: a randomized controlled trial

Effects of different levels of end-expiratory positive pressure on pulmonary dynamic compliance and alveolar-arterial oxygen partial pressure difference in patients undergoing gynecological laparoscopic surgery: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900021085
Enrollment
Unknown
Registered
2019-01-28
Start date
2019-03-10
Completion date
Unknown
Last updated
2019-02-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynecological tumors

Interventions

The control group:0peep
The experimental group1:5peep
The experimental group2:8peep
The experimental group3:10peep

Sponsors

Medical Ethics Committee of Affiliated Hospital of North Sichuan Medical College
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective gynecological laparoscopic surgery; 2. ASA level I to II; 3. Aged 18 to 60 years; 4. BMI18-28 kg/m2; 5. Gigned the informed consent of the test.

Exclusion criteria

Exclusion criteria: 1. History of heart disease; 2. History of lung surgery; 3. Respiratory diseases: such as pulmonary infection, COPD, asthma, chronic bronchitis, bronchiectasis, etc.; 4. History of smoking; 5. Chest deformity; 6. Contraindications to general anesthesia.

Design outcomes

Primary

MeasureTime frame
alveolar-arterial oxygen difference;dynamic compliance;—

Secondary

MeasureTime frame
Mean arterial pressur;Heart rate;Peak airway pressure;—

Countries

China

Contacts

Public ContactBin Chen

Medical Ethics Committee of Affiliated Hospital of North Sichuan Medical College

154024348@qq.com+86 13990799565

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026