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A multi-center randomized controlled trial for 5-Reductase Inhibitors in promoting wound healing following thulium laser resection of prostate

A multi-center randomized controlled trial for 5-Reductase Inhibitors in promoting wound healing following thulium laser resection of prostate

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900021072
Enrollment
Unknown
Registered
2019-01-27
Start date
2019-02-01
Completion date
Unknown
Last updated
2021-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign Prostatic Hyperplasia

Interventions

Experimental Group:taking finasteride

Sponsors

Shanghai General Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
50 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Aged 50 to 85 years; 2. Corresponding to diagnosis standards of benign prostatic hyperplasia in "Guidelines for the diagnosis and treatment of urological diseases in China"; 3. Corresponding to indications of operation of benign prostatic hyperplasia in "Guidelines for the diagnosis and treatment of urological diseases in China"; 4. Meet one of the conditions: A serve LUTs, IPSS>7 points; B ineffective medication; C refuse medication; D Qmax 50ml; F No contraindication for operation or finasteride.

Exclusion criteria

Exclusion criteria: 1. Taking aspirin or NSADS 2 weeks before inception; 2. Taking hormone drugs 6 months before inception or taking 5-reductase inhibitors 3 months before inception; 3. Accompanied urethrostenosis/neurogenic bladder/current UTI/history of operations about prostate/bladder neck/urethra; 4. Uncontrolled medical conditions; 5. Postoperative pathology reports are prostate cancer or other prostate diseases.

Design outcomes

Primary

MeasureTime frame
Complications;

Secondary

MeasureTime frame
IPSS;QoL;IIEF-5;urinary cytokines;urinalysis;urine culture;

Countries

China

Contacts

Public ContactShujie Xia

Shanghai General Hospital

xsjurologist@163.com+86 13761258811

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026