Alzheimer’s disease
Conditions
Interventions
Group 1:tDCS therapy
Group 2:sham treatment tDCS
Group 3:Cognitive care with real tDCS
Group 4:rTMS therapy
Group 5:sham treatment rTMS
Group 6:Cognitive care with real rTMS
Sponsors
Ningbo Kangning Hospital
Eligibility
Sex/Gender
All
Age
55 Years to 85 Years
Inclusion criteria
Inclusion criteria: The National Institute of Aging and the Alzheimer's Associations newly revised Diagnostic Criteria for AD (NIA-AA) in 2011 and the Vizamyl-PET age spot imaging gold standard were used as the main basis for enrollment, combining clinical and cognitive criteria (by Guardian or clinician).
Exclusion criteria
Exclusion criteria: Have had other neurological diseases (including stroke, optic myelitis, Parkinson's disease, epilepsy, etc.) and ruled out possible vascular, traumatic, medical-induced cognitive decline, unstable or severe heart, lung, liver Diseases of the kidney, hematopoietic system (including unstable angina, uncontrollable asthma, active gastric bleeding, cancer, etc.) and the presence of audiovisual impairments cannot be completed by neuropsychological tests and rating scales. The age of enrollment was 65-80 years old and the race was unanimous. There was no statistical difference between the groups. No antibiotics and alcohol abuse were used in the past month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mini-mental State Examination,MMSE;Alzheimer's disease assessment scale,ADAS-cog;Wechsler Adult Intelligence Scale;Transcranial Doppler Assessment;Caregiver Burden Inventory, CBI; | — |
Countries
China
Contacts
Public ContactHong Zheng
Ningbo Kangning Hospital
Outcome results
None listed