ß Lactam Drugs
Conditions
Interventions
Case Series:N/A
Sponsors
Department of Otolaryngology, West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Inpatients with a complaint of drug allergy to ß lactam antibiotics in West China Hospital from August 2017 to August 2018; 2. Aged 18 to 60 years, male or female; 3. Patients must sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe heart disease; 2. Uncontrolled asthma (FEV1<70%); 3. Hypertension patients taking ß receptor blocker and/or ACEI; 4. Patients history indicates severe delayed allergic reaction. Allergy happens 1 hour later or even several days after having medicine, including Stevens-Johnson syndrome, toxic epithelial necrolysis, exfoliative dermatitis and DRESS syndrome; 5. Psychological disorder; 6. Patients experienced allergic shock after using penicillin or having a skin test of penicillin within 10 years.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum specific IgE;skin prick test;intradermal test;oral challenge test;basophil activation test; | — |
Countries
China
Contacts
Public ContactMeng Juan
Department of Otolaryngology, West China Hospital, Sichuan University
Outcome results
None listed