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Do endometrial leucocytes and angiogenesis in the peri-implantation period predict hypertensive disorders in the subsequent pregnancy?

Do endometrial leucocytes and angiogenesis in the peri-implantation period predict hypertensive disorders in the subsequent pregnancy?

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900021046
Enrollment
Unknown
Registered
2018-12-18
Start date
2018-12-27
Completion date
Unknown
Last updated
2019-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Interventions

Gold Standard:Clinical outcome
Index test:endometrial&#32
leucocytes&#32
and&#32
angiogenesis&#32
markers

Sponsors

Prince of Whales Hospital, Chinese University of Hong Kong
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Women with a history of reproductive failure, including infertility, recurrent implantation failure and recurrent miscarriage; 2. Women younger than 40 years old.

Exclusion criteria

Exclusion criteria: 1. Women who have any uterine anomaly (such as fibroid and adenomyosis) or intrauterine pathology (such as polyp and intrauterine adhesion); 2. Hydrosalpinx; 3. Women diagnosed as hypertension prior to the endometrial biopsy.

Design outcomes

Primary

MeasureTime frame
the presence of uNK cells;pregnancy outcome;—

Secondary

MeasureTime frame
endometrial markers;hormonal and biochemical molecules;—

Countries

China

Contacts

Public ContactXiaoyan Chen

Prince of Whales Hospital, Chinese University of Hong Kong

chenxiaoyan@cuhk.edu.hk+852 59334979

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026