Lung Cancer
Conditions
Interventions
Experimental group:Sufentanil+Naloxone+Palonosetron
Control group:Sufentanil+Palonosetron
Sponsors
The First Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Lung cancer resection patientsunder general anesthesia; 2. Aged 18 to 65 years; 3. ASA classification I-II; 4. Understand the informed consent and agree to sign the informed consent before the study.
Exclusion criteria
Exclusion criteria: 1. Patients with severe cardiopulmonary disease and liver and kidney disease; 2. Allergic patients to naloxone; 3. Patients with opioid addiction or history of drug abuse; 4. The expected survival time after operation is less than 24 hours; 5. Vertigo patients; 6. The reasons why researchers think it is inappropriate to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NK cellc cytotoxicity;CD4+/CD8+;WBC count;Neutrophil percentage; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain VAS;postoperative nausea and vomiting;Consumption of Postoperative analgesics; | — |
Countries
CHINA
Contacts
Public ContactWen QingPing
The First Affiliated Hospital of Dalian Medical University
Outcome results
None listed