Lung tumor
Conditions
Interventions
low dose methylprednisolone:injevt 40mg methylprednisolone introvenous
high dose methylprednisolone:injevt 120mg methylprednisolone introvenous
control group :injevt normal saline introvenous
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged at least 18 years; 2. ASA I ~ III; 3. Selective thoracoscopic pneumonectomy; 4. Signing informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with gastrointestinal ulcer or allergic reaction; 2. Diabetic patients; 3. Long-term use of glucocorticoids before operation; 4. Chronic pain existed before operation. 5. Re-operation or conversion to thoracotomy is needed; 6. Postoperative admission to ICU.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the proportion of moderate-to-severe pain on the first day postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| pain scores within 3 days after surgery;the rate of post-operative nausea and vomitting;postoperative quality of recovery scores;IL-6, CRP, and fasting blood sugar;Length of hospital stay;the rate of rescue analgesia; | — |
Countries
China
Contacts
Public ContactHai Yu
37 Guoxue Lane, Wuhou District, Chengdu, Sichuan, China
Outcome results
None listed