neonatal respiratory distress syndrome
Conditions
Interventions
LISA group:surfactant administration by LISA
Low pressure support group:surfactant administration by low pressure
Sponsors
Women's Hospital, School of Medicine, Zhejiang University
Eligibility
Sex/Gender
All
Age
No minimum to 1 Years
Inclusion criteria
Inclusion criteria: 1. 25+0 weeks to 31+6 weeks gestational age with 600g-1500g birth body weight; 2. toleranted with non-invasive respiratory support; 3. within 6 hours after birth; 4. indicated to receive surfactant; 5. signed informed content by parents.
Exclusion criteria
Exclusion criteria: 1. need intubation before trial; 2. obvious congenital malformations or chromosomal diseases; 3. neuromuscular diseases affecting respiratory function; 4. Congenital pulmonary infection or pulmonary dysplasia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mortality at 36 weeks of corrected gestational age;Incidence and extent of bronchopulmonary dysplasia; | — |
Secondary
| Measure | Time frame |
|---|---|
| vital signs during procedure;operation failure;mobidity of associated diseasesduring hospitalizatio;respiratory mode after surfactant administration; | — |
Countries
China
Contacts
Public ContactJiajunzhu ZHU
Women's Hospital, School of Medicine, Zhejiang University
Outcome results
None listed